Great Lakes Regional Center of Excellence

Great Lakes Regional Center of Excellence

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2008 GLRCE Publications

Past years

2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003

Budzik JM, Oh SY, Schneewind O. 2008. Cell wall anchor structure of BcpA pili in Bacillus anthracis. J. Biol. Chem. 283:36676-86.
Full article on PubMedCentral
PMID: 18940793 PMCID: PMC2605976

Zhou Z, Khaliq M, Suk JE, Patkar C, Li L, Kuhn RJ, Post CB. 2008. Antiviral compounds discovered by virtual screening of small-molecule libraries against dengue virus E protein. ACS Chem. Biol. 3:765-75.
Full article on PubMedCentral
PMID: 19053243 PMCID: PMC2782732

Unger B, Nichols RJ, Stanitsa ES, Traktman P. 2008. Functional characterization of the vaccinia virus I5 protein. Virol. J. 5:148.
Full article on PubMedCentral
PMID: 19077320 PMCID: PMC2621143

Blaylock B, Sorg JA, Schneewind O. 2008. Yersinia enterocolitica type III secretion of YopR requires a structure in its mRNA. Mol. Microbiol. 70:1210-22.
Pubmed Abstract
PMID: 18976277

Cornelius CA, Quenee LE, Overheim KA, Koster F, Brasel TL, Elli D, Ciletti NA, Schneewind O. 2008. Immunization with recombinant V10 protects cynomolgus macaques from lethal pneumonic plague. Infect. Immun. 76:5588-97.
Full article on PubMedCentral
PMID: 18794281 PMCID: PMC2583586

Dong M, Liu H, Tepp WH, Johnson EA, Janz R, Chapman ER. 2008. Glycosylated SV2A and SV2B mediate the entry of botulinum neurotoxin E into neurons. Mol. Biol. Cell 19:5226-37.
Full article on PubMedCentral
PMID: 18815274 PMCID: PMC2592654

Iyer AV, Blinkova AL, Yang SY, Harrison M, Tepp WH, Jacobson MJ, Johnson EA, Bennett GN, Walker JR. 2008. Clostridium taeniosporum is a close relative of the Clostridium botulinum Group II. Anaerobe 14:318-24.
Pubmed Abstract
PMID: 19135540

Pfleger BF, Kim Y, Nusca TD, Maltseva N, Lee JY, Rath CM, Scaglione JB, Janes BK, Anderson EC, Bergman NH, Hanna PC, Joachimiak A, Sherman DH. 2008. Structural and functional analysis of AsbF: origin of the stealth 3,4-dihydroxybenzoic acid subunit for petrobactin biosynthesis. Proc. Natl. Acad. Sci. U.S.A. 105:17133-8.
Full article on PubMedCentral
PMID: 18955706 PMCID: PMC2579390

Garufi G, Butler E, Missiakas D. 2008. ESAT-6-like protein secretion in Bacillus anthracis. J. Bacteriol. 190:7004-11.
Full article on PubMedCentral
PMID: 18723613 PMCID: PMC2580693

Bhattacharya D, Hoover S, Falk SP, Weisblum B, Vestling M, Striker R. 2008. Phosphorylation of yellow fever virus NS5 alters methyltransferase activity. Virology 380:276-84.
Full article on PubMedCentral
PMID: 18757072 PMCID: PMC2583469

Depaolo RW, Tang F, Kim I, Han M, Levin N, Ciletti N, Lin A, Anderson D, Schneewind O, Jabri B. 2008. Toll-like receptor 6 drives differentiation of tolerogenic dendritic cells and contributes to LcrV-mediated plague pathogenesis. Cell Host Microbe 4:350-61.
Full article on PubMedCentral
PMID: 18854239 PMCID: PMC2633104

Clay CD, Soni S, Gunn JS, Schlesinger LS. 2008. Evasion of complement-mediated lysis and complement C3 deposition are regulated by Francisella tularensis lipopolysaccharide O antigen. J. Immunol. 181:5568-78.
Full article on PubMedCentral
PMID: 18832715 PMCID: PMC2782685

Nichols RJ, Stanitsa E, Unger B, Traktman P. 2008. The vaccinia virus gene I2L encodes a membrane protein with an essential role in virion entry. J. Virol. 82:10247-61.
Full article on PubMedCentral
PMID: 18701587 PMCID: PMC2566298

Cremer TJ, Tridandapani S. 2008. Effective host response to Francisella tularensis requires functional mast cells. 3:503-6.
Full article on PubMedCentral
PMID: 18811234 PMCID: PMC2572753

Rajashekara G, Covert J, Petersen E, Eskra L, Splitter G. 2008. Genomic island 2 of Brucella melitensis is a major virulence determinant: functional analyses of genomic islands. J. Bacteriol. 190:6243-52.
Full article on PubMedCentral
PMID: 18641138 PMCID: PMC2546784

Turner JK, McAllister MM, Xu JL, Tapping RI. 2008. The resistance of BALB/cJ mice to Yersinia pestis maps to the major histocompatibility complex of chromosome 17. Infect. Immun. 76:4092-9.
Full article on PubMedCentral
PMID: 18573896 PMCID: PMC2519398

Taft SC, Weiss AA. 2008. Toxicity of anthrax toxin is influenced by receptor expression. Clin. Vaccine Immunol. 15:1330-6.
Full article on PubMedCentral
PMID: 18596206 PMCID: PMC2546661

Prochazkova K, Satchell KJ. 2008. Structure-function analysis of inositol hexakisphosphate-induced autoprocessing of the Vibrio cholerae multifunctional autoprocessing RTX toxin. J. Biol. Chem. 283:23656-64.
Pubmed Abstract
PMID: 18591243

Dings RP, Haseman JR, Mayo KH. 2008. Probing structure-activity relationships in bactericidal peptide betapep-25. Biochem. J. 414:143-50.
Pubmed Abstract
PMID: 18489259

Li Z, Khaliq M, Zhou Z, Post CB, Kuhn RJ, Cushman M. 2008. Design, synthesis, and biological evaluation of antiviral agents targeting flavivirus envelope proteins. J. Med. Chem. 51:4660-71.
Full article on PubMedCentral
PMID: 18610998 PMCID: PMC2562352

Mohapatra NP, Soni S, Reilly TJ, Liu J, Klose KE, Gunn JS. 2008. Combined deletion of four Francisella novicida acid phosphatases attenuates virulence and macrophage vacuolar escape. Infect. Immun. 76:3690-9.
Full article on PubMedCentral
PMID: 18490464 PMCID: PMC2493204

Burts ML, DeDent AC, Missiakas DM. 2008. EsaC substrate for the ESAT-6 secretion pathway and its role in persistent infections of Staphylococcus aureus. Mol. Microbiol. 69:736-46.
Full article on PubMedCentral
PMID: 18554323 PMCID: PMC2597432

Chen S, Hall C, Barbieri JT. 2008. Substrate recognition of VAMP-2 by botulinum neurotoxin B and tetanus neurotoxin. J. Biol. Chem. 283:21153-9.
Full article on PubMedCentral
PMID: 18511417 PMCID: PMC2475686

Budzik JM, Marraffini LA, Souda P, Whitelegge JP, Faull KF, Schneewind O. 2008. Amide bonds assemble pili on the surface of bacilli. Proc. Natl. Acad. Sci. U.S.A. 105:10215-20.
Full article on PubMedCentral
PMID: 18621716 PMCID: PMC2481347

Riordan KE, Sorg JA, Berube BJ, Schneewind O. 2008. Impassable YscP substrates and their impact on the Yersinia enterocolitica type III secretion pathway. J. Bacteriol. :.
Full article on PubMedCentral
PMID: 18641141 PMCID: PMC2546781

Chen C, Baldwin MR, Barbieri JT. 2008. Molecular basis for tetanus toxin coreceptor interactions. Biochemistry 47:7179-86.
Full article Pubmed Abstract
PMID: 18543947

Pechous RD, McCarthy TR, Mohapatra NP, Soni S, Penoske RM, Salzman NH, Frank DW, Gunn JS, Zahrt TC. 2008. A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge. PLoS ONE 3:e2487.
Full article on PubMedCentral
PMID: 18575611 PMCID: PMC2429968

Parsa KV, Butchar JP, Rajaram MV, Cremer TJ, Gunn JS, Schlesinger LS, Tridandapani S. 2008. Francisella gains a survival advantage within mononuclear phagocytes by suppressing the host IFNgamma response. Mol. Immunol. 45:3428-37.
Full article on PubMedCentral
PMID: 18514317 PMCID: PMC2577832

Perera R, Khaliq M, Kuhn RJ. 2008. Closing the door on flaviviruses: Entry as a target for antiviral drug design. Antiviral Res. :.
Full article on PubMedCentral
PMID: 18585795 PMCID: PMC2646114

Riordan KE, Schneewind O. 2008. YscU cleavage and the assembly of Yersinia type III secretion machine complexes. Mol. Microbiol. 68:1485-501.
Full article Pubmed Abstract
PMID: 18452514

Roth KM, Oghumu S, Satoskar AA, Gunn JS, van Rooijen N, Satoskar AR. 2008. Respiratory infection with Francisella novicida induces rapid dystrophic cardiac calcinosis (DCC). FEMS Immunol. Med. Microbiol. 53:72-8.
Pubmed Abstract
PMID: 18400010

Gunn JS. 2008. The Salmonella PmrAB regulon: lipopolysaccharide modifications, antimicrobial peptide resistance and more. Trends Microbiol. 16:284-90.
Pubmed Abstract
PMID: 18467098

Parsa KV, Butchar JP, Rajaram MV, Cremer TJ, Tridandapani S. 2008. The tyrosine kinase Syk promotes phagocytosis of Francisella through the activation of Erk. Mol. Immunol. 45:3012-21.
Full article on PubMedCentral
PMID: 18295889 PMCID: PMC2408723

Rambow-Larsen AA, Rajashekara G, Petersen E, Splitter G. 2008. Putative quorum-sensing regulator BlxR of Brucella melitensis regulates virulence factors including the type IV secretion system and flagella. J. Bacteriol. 190:3274-82.
Full article on PubMedCentral
PMID: 18310341 PMCID: PMC2347389

Quenee LE, Cornelius CA, Ciletti NA, Elli D, Schneewind O. 2008. Yersinia pestis caf1 variants and the limits of plague vaccine protection. Infect. Immun. 76:2025-36.
Full article on PubMedCentral
PMID: 18347051 PMCID: PMC2346721

Viola RE, Yerman L, Fowler JM, Arvidson CG, Brubaker RR. 2008. A missense mutation causes aspartase deficiency in Yersinia pestis. Microbiology (Reading, Engl.) 154:1271-80.
Full article Pubmed Abstract
PMID: 18451035

Jonathan P. Butchar, Murugesan V.S. Rajaram, Kishore V.L. Parsa, Corey D. Clay, John S. Gunn, Larry S. Schlesinger, and Susheela Tridandapani. 2008. IL-23 aids in defense against Francisella infection. FASEB J. 22:675.14.

Thomas John Cremer, Melissa G. Hunter, Terry S. Elton, Clay B. Marsh, Susheela Tridandapani, and Jonathan P. Butchar. 2008. microRNA influence on host response to Francisella infection. FASEB J. 22:1065.9.

Butchar JP, Parsa KV, Marsh CB, Tridandapani S. 2008. IFNgamma enhances IL-23 production during Francisella infection of human monocytes. FEBS Lett. 582:1044-8.
Full article on PubMedCentral
PMID: 18319062 PMCID: PMC2376054

Nawabi P, Catron DM, Haldar K. 2008. Esterification of cholesterol by a type III secretion effector during intracellular Salmonella infection. Mol. Microbiol. 68:173-85.
Full article Pubmed Abstract
PMID: 18333886

Kern JW, Schneewind O. 2008. BslA, a pXO1-encoded adhesin of Bacillus anthracis. Mol. Microbiol. 68:504-15.
Full article Pubmed Abstract
PMID: 18366441

Hoover S, Striker R. 2008. Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner. J. Gen. Virol. 89:1000-9.
Pubmed Abstract
PMID: 18343842

Yu IM, Zhang W, Holdaway HA, Li L, Kostyuchenko VA, Chipman PR, Kuhn RJ, Rossmann MG, Chen J. 2008. Structure of the immature dengue virus at low pH primes proteolytic maturation. Science 319:1834-7.
Full article Pubmed Abstract
PMID: 18369148

Li L, Lok SM, Yu IM, Zhang Y, Kuhn RJ, Chen J, Rossmann MG. 2008. The flavivirus precursor membrane-envelope protein complex: structure and maturation. Science 319:1830-4.
Full article Pubmed Abstract
PMID: 18369147

Yamayoshi S, Noda T, Ebihara H, Goto H, Morikawa Y, Lukashevich IS, Neumann G, Feldmann H, Kawaoka Y. 2008. Ebola virus matrix protein VP40 uses the COPII transport system for its intracellular transport. Cell Host Microbe 3:168-77.
Full article on PubMedCentral
PMID: 18329616 PMCID: PMC2330329

Baldwin MR, Tepp WH, Przedpelski A, Pier CL, Bradshaw M, Johnson EA, Barbieri JT. 2008. Subunit vaccine against the seven serotypes of botulism. Infect. Immun. 76:1314-8.
Full article on PubMedCentral
PMID: 18070903 PMCID: PMC2258812

Lok SM, Kostyuchenko V, Nybakken GE, Holdaway HA, Battisti AJ, Sukupolvi-Petty S, Sedlak D, Fremont DH, Chipman PR, Roehrig JT, Diamond MS, Kuhn RJ, Rossmann MG. 2008. Binding of a neutralizing antibody to dengue virus alters the arrangement of surface glycoproteins. Nat. Struct. Mol. Biol. 15:312-7.
Full article Pubmed Abstract
PMID: 18264114

Castorena KM, Peltier DC, Peng W, Miller DJ. 2008. Maturation-dependent responses of human neuronal cells to western equine encephalitis virus infection and type I interferons. Virology 372:208-20.
Full article Pubmed Abstract
PMID: 18022665

Maresso AW, Schneewind O. 2008. Sortase as a target of anti-infective therapy. Pharmacol. Rev. 60:128-41.
Full article Pubmed Abstract
PMID: 18321961

Bielinska AU, Chepurnov AA, Landers JJ, Janczak KW, Chepurnova TS, Luker GD, Baker JR. 2008. A novel, killed-virus nasal vaccinia virus vaccine. Clin. Vaccine Immunol. 15:348-58.
Full article on PubMedCentral
PMID: 18057181 PMCID: PMC2238057

Halfmann P, Kim JH, Ebihara H, Noda T, Neumann G, Feldmann H, Kawaoka Y. 2008. Generation of biologically contained Ebola viruses. Proc. Natl. Acad. Sci. U.S.A. 105:1129-33.
Full article on PubMedCentral
PMID: 18212124 PMCID: PMC2234103

Taft SC, Weiss AA. 2008. Neutralizing activity of vaccine-induced antibodies to two Bacillus anthracis toxin components, lethal factor and edema factor. Clin. Vaccine Immunol. 15:71-5.
Full article on PubMedCentral
PMID: 18032590 PMCID: PMC2223847

Pier CL, Tepp WH, Bradshaw M, Johnson EA, Barbieri JT, Baldwin MR. 2008. Recombinant holotoxoid vaccine against botulism. Infect. Immun. 76:437-42.
Full article on PubMedCentral
PMID: 17967862 PMCID: PMC2223665

Pollard AM, Onatolu KN, Hiller L, Haldar K, Knoll LJ. 2008. Highly polymorphic family of glycosylphosphatidylinositol-anchored surface antigens with evidence of developmental regulation in Toxoplasma gondii. Infect. Immun. 76:103-10.
Full article on PubMedCentral
PMID: 17938221 PMCID: PMC2223667

Butchar JP, Cremer TJ, Clay CD, Gavrilin MA, Wewers MD, Marsh CB, Schlesinger LS, Tridandapani S. 2008. Microarray analysis of human monocytes infected with Francisella tularensis identifies new targets of host response subversion. PLoS ONE 3:e2924.
Full article on PubMedCentral
PMID: 18698339 PMCID: PMC2488368

Roark EA, Haldar K. 2008. Effects of lysosomal membrane protein depletion on the Salmonella-containing vacuole. PLoS ONE 3:e3538.
Full article on PubMedCentral
PMID: 18958159 PMCID: PMC2568857

Past years

2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003

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